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May 13, 2002 · Finally, ectopic T-bet did not directly induce expression of endogenous T- bet independently of IFN-γ or STAT1. Thus, T-bet is induced by IFN-γ and STAT1 signaling during T cell activation. In ...This rapid induction of T-bet at low IFN-γ levels emphasized the role of IFN-γ in biologically relevant conditions. Moreover, this suggested that activation of Stat1 is necessary, but not sufficient, for T-bet induction by IFN-γ. Figure 4. T-bet mRNA is induced specifically by IFN-γ …Easily become a member of Betway Sports by using your smartphone or tablet device. We offer online betting from any device, making it easy for you to log online, at home or on the go. With a seamless design and simple controls, you can use our sports betting app to place wagers on the NFL, MLB, NBA, NHL and many other professional sports.Check out the best betting community in the world. 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