How to taper lamictal

If you feel okay you could try another 10% reduction sooner than the 4 weeks, eg between 2-3 weeks after. I think tapering carefully would be better than risking too fast a taper. Removal of lamotrigine can cause a nasty rebound of "alerting," i.e. anxiety, restlessness, and sleeplessness.

OXcarbazepine food. Applies to: Trileptal (oxcarbazepine) Alcohol can increase the nervous system side effects of OXcarbazepine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with OXcarbazepine.A psychiatrist will be able to recognize and treat symptomatic relapse and adverse reactions in withdrawal - as well as recommend a tapering protocol (if necessary). Vraylar tapering or transition: Vraylar is a medication that can cause severe withdrawal symptoms if discontinued suddenly (i.e. "cold turkey"). To prevent harsh withdrawal ...Jun 29, 2022 · Lamictal is a drug primarily used as a mood stabilizer. Lamictal is an anticonvulsant drug and is also used for treating seizures and epilepsy. It can be used alone or with other drugs to treat mood disorders and epilepsy. Lamictal Withdrawal Symptoms & Side Effects An empiric postpartum taper reduced the likelihood of maternal LTG toxicity (p < 0.05) (n = 27). Newborn outcomes were similar to the general population (n = 52). Conclusions: These novel data contribute to a rational treatment plan and dosing paradigm for lamotrigine use during pregnancy, parturition, and the postpartum period.Tapering Lamictal often runs into serious problems if not done carefully and slowly.. I took the taper schedule and stretched it, adding changes every 3 days; every other day. Lamictal is not thought to be an anti-manic drug along. and requires a long ramp-up period on a specific schedule.. more, then you will need to start all over and taper.Dr. Paul Pyles answered. 33 years experience Addiction Medicine. Talk to your doctor:You may need to taper the lamictal more slowly. Talk to your doctor. You may need a low dose of lamictal for a few weeks before stopping. You and you ... Read More. 3 doctors agree. 1.

Cross tapering is one of several ways of switching antidepressants. Many doctors prefer cross tapering, especially if you are switching between different types of antidepressants. Cross tapering allows you to avoid some of the most serious withdrawal symptoms. Cross tapering can be useful when you are changing from one type of antidepressant ...For example, tapering from 20 mg of diazepam at a rate of 10% a week would entail a 2 mg reduction in the first week. The second week's cumulative reduction would be 3·8 mg (a further 1·8 mg reduction), the third week's cumulative reduction would be 5·42 mg (a further 1·62 mg), and so on ().These exponentially decreasing regimens produce approximately …Lamotrigine taper questions. Hello, I have been on Lamictal for half a year now. I had an adverse reaction to the antidepressants I was taking which caused me to experience mania--I was then prescribed Lamictal for bipolar disorder. I do not think I am bipolar and Lamictal has only made my life worse--Lamictal makes me hostile, angry, and ...of volunteer peer support for tapering off psychiat-ric drugs and recovering from withdrawal syn-drome.5–12 Since 2011, under the pseudonym Altostrata, I have operated one of those online ... psychiatrist with tiny doses of lamotrigine, up to 1.5mg, to stabilize my nervous system. 27 Still, my recovery was extremely gradual; ultimately, IMar 8, 2021 · Lamotrigine (Lamictal) is not addictive. However, lamotrigine withdrawal seizures have been reported in patients when they stop taking lamotrigine abruptly or when they are on a rapid weaning off the drug. In addition, people who are taking lamotrigine to control mood swings from bipolar disorder may experience withdrawal seizures along with ... Lamotrigine is usually taken 1 or 2 times daily with or without food. Typically patients begin at a low dose of medication and the dose is increased slowly over several weeks. The dose usually ranges from 25 mg to 400 mg.So it's not that Lexapro has btaperined to Lamictal for me. My doctor is tapering off my Lamictal the same time she having me start Lexapro. I'm supposed to be on my second week of 50mg of Lamictal but my anxiety has gotten so bad I feel like I'm having a a heart attack, I've been experiencing tremors, lethargy, chest pain, headaches, cognitive problems, etc.

The Executive Management Team has extensive industry experience across a wide variety of How To Taper Off Lamictal 100mg and delivery methods. The majority of the Executive Management Team has worked together in Miami since the 1980's, producing hundreds of projects for our communities, building long-term and repeat business, and maintaining ...Initial dose: 0.6 mg/kg/day orally in 2 divided doses (week 1 and 2), then 1.2 mg/kg/day orally in 2 divided doses (week 3 and 4), then increase by 1.2 mg/kg/day every 1 to 2 weeks until optimal response is achieved. Usual maintenance dose: 5 to 15 mg/kg/day orally in 2 divided doses; Maximum dose: 400 mg/day.Initial dose: 0.6 mg/kg/day orally in 2 divided doses (week 1 and 2), then 1.2 mg/kg/day orally in 2 divided doses (week 3 and 4), then increase by 1.2 mg/kg/day every 1 to 2 weeks until optimal response is achieved. Usual maintenance dose: 5 to 15 mg/kg/day orally in 2 divided doses; Maximum dose: 400 mg/day.75mg isn't very high so that's why you were able to quit cold turkey. 300+ is standard and requires tapering off. I was just curious because I may ask my pdoc ...

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Starting Dose before tapering: 200mg Lamictal Tapering schedule: Started medication in August of 2018 January 1st 2023: 200mg to 175mg (25 mg drop) January 15th 2023: 175mg to 150mg (25mg drop) March 4th 2023: 150mg to 137.5 (12.5mg drop) March 11th 2023: 137.5mg to 131.25mg (6.25mg drop) March 16th 2023: 131.25mg to 125mg (6.25mg drop)Lamotrigine is a mood stabiliser that reduces fluctuations in mood among people with bipolar affective disorder and prevents episodes of depression in these patients. Compared with other mood stabilisers, lamotrigine is relatively safe in overdose. Two small-scale clinical trials of lamotrigine for people with BPD found improvements in ...Last Updated on August 9, 2022 by Carol Gillette. Alternative to Meds Editorial Team. Medically Reviewed by Dr Samuel Lee MD. Table of Contents: Common Reasons Doctors Prescribe Lamictal. Lamictal …Taper off extremely slowly or, as Papp suggested, "You can switch from a short half-life medication to fluoxetine (Prozac) and then taper down from that." Gradually reducing the antidepressant agent with a long half-life has indeed been shown to reduce the severity of brain zaps and other kinds of discontinuation effects.

I took Lamictal for mood swings for about four weeks and only got up to fifty mg. I was having intrusive thoughts like crazy so I thought it would be a good idea to taper off without telling my psychiatrist. Dear God. I'm still going through withdrawals. I've stopped tapering and don't plan on going back on Lamictal ever again.Anyway the taper should be very slow. I cut out 25 mg and kept it there for a month. Now I cut out another 25mg. The more you rush it, the worst it gets. Also there is an amino acid which really ...Oct 1, 2019 · Stopping and switching antipsychotics can result in serious consequences, particularly a relapse of psychosis which may entail serious risks and worsen long-term prognosis. Withdrawal syndromes related to cholinergic and dopaminergic effects may occur depending on the characteristics of the antipsychotics involved. Start aripiprazole at 10 mg on day 1. Slowly increase aripiprazole over the next four weeks to the desired therapeutic dose during the period of cariprazine elimination. Dose range of aripiprazole for psychosis is 10-30 mg taken in the morning. Source: Keks N, Schwartz D, Hope J. Antipsychotic switching tool.Apr 1, 2021 · The tapering schedule should ideally be provided by a neurologist after taking all relevant factors into account and discussing them with the patient. The taper duration will also be influenced by the patient’s needs and preferences. 10 A slow taper (e.g. over months) allows observation and helps to document the minimally effective doses in ... It seems different for everyone. I noticed effects pretty much as soon as I started on 25mg, and even more so when I increased dosage a few days ago to 50mg, but I've seen others say weeks or over a month. And some say they feel worse with dosage increase for a few weeks then all of a sudden feel like it's working great.tapering off lamictal . Long-Term User (1 year+) Has anyone had any success or tips on how to successfully taper off lamictal 200 mg? I've been on it for 5 years and it's hard to even taper down to 150 mg a day without horrible depressive and anxiety symptoms. ShareAs with other drugs, we recommend very gradual tapering at 10% per month, based on the current dosage (the amount of the decrease keeps getting smaller). Read …Hey everyone I need to taper off of Lamictol. It works well and no complaints. I was misdiagnosed and am going to work on issues with a therapist. I tried to taper before and the anxiety was insane. I guess thats a part of it. I was thinking 25mg every week for two months. I am on 200MG. Thank you!I am here to get information on tapering lamictal. The last time i tried to reduce dosage i ended up with some anger and increased muscle pain and cramping. I wasn't sure if it was connected, but since reinstating my dose, those issues have gone away. I initially reduced by 20%. Next time i will reduce by 10%. - something i learned here.

What I did was taper down from my starting dose, then increase 50 mg at a time. I was in month two when the itch became uncomfortable enough to deal with it. I was on lamictal and an SSRI. Years later, when I wanted to test the waters without the mood stableizer of Lamictal, the withdrawal was inhuman, fyi. Reply reply

Lamotrigine and lithium were effective monotherapy for BDII depression, with comparable response and remission rates. Naturalistic design and lack of placebo limit conclusions, though patient history indicated long standing depression unlikely to be alleviated by time. ... and randomization scheduled to coincide with the last day of the taper ...Monitor these symptoms closely, especially within 1 to 4 days after a reduction in dosage. Slowing the taper is recommended to avoid serious or lingering adverse reactions. 33,34. Ativan tapering may be the most difficult at the end. Do not be dismayed if your Ativan taper becomes more difficult after the halfway point. This is not …I am also on Effexor XR and Lamictal. My doctor added a small dose of Lamictal to the mix, because Effexor seemed to lose its effect. I am not bipolar. I also have problems with concentration, but I believe I had problems with concentration previously, as it is a common syptom of depression. Best wishes!I fucking hate Lamictal. I started taking it a couple of months ago, but recently decided to stop due to the severe memory loss and brain fog it gave me on only 100 mg. During the peak of it, I was unable to remember a majority of my day by the end of it. I wouldn't be able to remember a 4-digit sequence past a few seconds.Discontinuing lithium abruptly or in less than 2 weeks, rather than tapering (> 2 weeks) doubles the risk of a recurrent mood episode in 1 year; and the risk increases by 20 times in 3 years. At least 1 month should be spent tapering off lithium. Abrupt discontinuation of lithium and may actually exceed that of the risk of the untreated disorder.How to taper medication in adults (4) seek expert advice; discuss the possibility of gradually withdrawing therapy with the patient. Medication should be tapered off gradually; if the dose is reduced gradually then withdrawal features such as recurrent seizures, and rarer symptoms such as anxiety and restlessness can usually be avoidedLamictal withdrawal blows! I'm doing a slow taper. I had no problem gradually dropping from 400 to 150mg over a few months, but now I'm ready to actually taper off. 150 go 100 was fine until day 5, where I had am absolute freak out and was convinced that there were bugs all over me. Increasing my dose of haldol has mostly solved that but I ...This has now been shown with lithium and as well as with some other drugs. [3,4] In bipolar you may be switching medications fairly frequently depending on the patient's symptoms. As long as the side effects aren't intolerable and there are no medical issues, you would want to taper over a couple of weeks.

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Business, Economics, and Finance. GameStop Moderna Pfizer Johnson & Johnson AstraZeneca Walgreens Best Buy Novavax SpaceX Tesla. CryptoIn most cases, patients can safely taper off the drug by simply following the specific instructions given by their healthcare provider. Patients taking Lamictal together with other antiepileptic drugs should also be reevaluated for all other medications currently taken in case of adverse reactions or change in seizure control following Lamictal ...This webinar will review new and existing topical prescription treatments available, how to safely start and taper off steroids and which topicals are better for certain parts of y...Antipsychotic switching strategies (a) abrupt discontinuation of the current antipsychotic and immediate implementation of the new antipsychotic; (b) gradual cross-tapering of the current antipsychotic and the new antipsychotic; (c) continuation of the first antipsychotic at full dose while gradually tapering the new antipsychotic up to the ...Lamotrigine can be used to treat the following partial seizures, primary generalized tonic-clonic seizures, bipolar I disorder maintenance and Lennox-Gastaut syndrome. Off-label uses include treating acute bipolar depression, fibromyalgia, schizophrenia, and unipolar depression. This activity covers lamotrigine, including mechanism of action, pharmacology, adverse event profiles, eligible ...Lamotrigine has been shown to be useful in the long-term prophylaxis of depressive episodes in BD. Current guidelines recommend discontinuing lamotrigine in patients who develop rash. Our objective in this paper is to review literature to identify possible predictors of serious vs. benign rash that might help guide clinical decision-making and ...Brain zaps feel like an electric shock in the brain, which happens after stopping antidepressant use. Brain zaps typically happen if you move your eyes and head. Some people report feeling dizzy ...The usual maintenance dose ranges from 200 to 400 mg per day. When using extended release tablets, the maintenance dosage ranges from 200 to 600 mg taken once a day. Again, the dose should be slowly titrated until the effective dose is achieved. Pediatric patients (2 to 12 years of age) are given an adjusted dose of Lamictal based on the ...Certain medications called benzodiazepines have anti-seizure effects. These include the drugs clonazepam, clobazam, diazepam, lorazepam, and clorazepate. They are effective at stopping prolonged seizures or clusters of seizures. But, taking them daily may cause drowsiness, dizziness and loss of balance, and other side effects.It's advised to follow a tapering plan, reducing lamotrigine doses gradually over a minimum of 4 weeks (with medical supervision) to avoid bipolar relapses and withdrawal symptoms like: Mood swings. Difficulties with memory, judgement, thinking & learning. Headaches.Dose reduction q 2 months: carbamazepine 100 mg; oxcarbazepine 150 mg; phenytoin 50 mg; lamotrigine, 25 mg; topiramate, 25 mg; levetiracetam, 250 mg and zonisamide, 50 mg. > 80% of relapse during taper occurred within 2 months of dose reduction. 25% of patients attempting to discontinue AED relapsed. ….

I have as of 3 weeks started tapering off the lamotrigine. I have had rather awful experiences such as severe panic attacks, insomnia, paranoia and depression. I also had racing thoughts, extreme fear and outbursts of anger. I am a lot better now and feeling more clear minded than I ever felt.• Lamotrigine has proven efficacy in the maintenance phase of treatment for bipolar disorder and has been shown to significantly increase the time between major mood episodes. • Factors that increase the risk of a rash with lamotrigine use include rapid titra-tion, exceeding the maximum recommended dosage, and concomitant use of valproate.Medications used as mood stabilizers (Lamictal, Tegretol, Depakote, etc.) are actually classed as anticonvulsants. The only true mood stabilizer is lithium. It was wise of your doctor to alert you to the possibility of a seizure, but it's pretty unlikely. I came off lamotrigine over two weeks and had no problems at all.Taper off extremely slowly or, as Papp suggested, "You can switch from a short half-life medication to fluoxetine (Prozac) and then taper down from that." Gradually reducing the antidepressant agent with a long half-life has indeed been shown to reduce the severity of brain zaps and other kinds of discontinuation effects.i'm off. have been ever since. med free by choice. 100mg, quit CT. most people recommend a taper of 5% of your dose until you stabilize, then you can drop again. it took me a year after quitting to feel normal again, but i have some permanent food allergies as a result. join the lamictal withdrawal group on facebook. there's a wealth of info there and tips on how to cope with withdrawal ...I've tried multiple times to taper off Lamictal (dose 200mg) without doctor's or psychiatrists aid (due to inability to afford medical appointments... fun). i've been on lamictal for about 2 years I think - hard to tell tbh because i find my memory recall, both long and short, to be pretty hazy.Lamictal needs to be tapered very slowly. I didn’t know just how slowly when this post was first written. Towards the end of the taper I got children’s doses of Lamictal in 1 and 2 mg because the sensitive body feels even smaller tapers. I made a liquid suspension (with the help of a compounding pharmacy and actually cut by fractions of a mg.... LAMICTAL. Unless safety concerns require a more rapid withdrawal, the dose of LAMICTAL should be tapered over a period of at least 2 weeks (approximately 50 ...I have always wanted a clinical tool that offered a blueprint for cross-tapering from one antipsychotic medication to another, and particularly one that took medication half-life into account. A drug like aripiprazole with a 75 hour half-life is going to linger much longer than a short half-life medication like quetiapine (t½ ≈ 6 hours). How to taper lamictal, Seroquel ( quetiapine ) is an atypical antipsychotic medication that is FDA approved for the treatment of schizophrenia and mixed bipolar episodes in adults. It can be prescribed for schizophrenia for children over the age of 12. 7 Bipolar may include either acute manic or depressive episodes., Medications such as valproic acid and lamotrigine are also indicated for mood stabilization in patients with bipolar disorder, and topiramate is commonly used in managing headache disorders. ... The authors defined a “slow” taper as occurring over more than 3 months, whereas a “rapid” taper was defined as occurring within 3 months …, Abstract. If lamotrigine (LTG) has to be replaced with valproate (VPA), this exchange may be complicated by adverse events that result from the complex interaction of both drugs. We report on two cases in which such problems occurred in spite of a cautious switch considering the VPA induced LTG serum increase., Anti-epileptic drugs such as APX-LAMOTRIGINE are used to treat epilepsy. It is used for the treatment of epilepsy in patients over 2 years of age. In general, it is initially used in addition to other medicines, for the treatment of epilepsy including partial or generalized seizures and Lennox- Gastaut syndrome., Discontinuing lithium abruptly or in less than 2 weeks, rather than tapering (> 2 weeks) doubles the risk of a recurrent mood episode in 1 year; and the risk increases by 20 times in 3 years. At least 1 month should be spent tapering off lithium. Abrupt discontinuation of lithium and may actually exceed that of the risk of the untreated disorder., For more information, learn about epilepsy or visit our resources section. Keppra & Lamictal Combination. Thu, 07/19/2007 - 14:26. Topic: Medication Issues. Any greater side effects from taking a combination of both medications together may worsen especially when taken at doses Keppra 500mg. ( 2morn. 2 eve.) Lamictal 100mg (3morn 3 eve.), Lamotrigine has been shown to be useful in the long-term prophylaxis of depressive episodes in BD. Current guidelines recommend discontinuing lamotrigine in patients who develop rash. Our objective in this paper is to review literature to identify possible predictors of serious vs. benign rash that might help guide clinical decision-making and ..., What is Lamictal? Lamictal, also known by its generic name lamotrigine, is a medication primarily prescribed to treat epilepsy and bipolar disorder.It belongs to a class of drugs known as anticonvulsants or antiepileptic drugs. Lamictal works by stabilizing abnormal electrical activity in the brain, which can help prevent seizures and manage symptoms associated with bipolar disorder., The usual maintenance dose ranges from 200 to 400 mg per day. When using extended release tablets, the maintenance dosage ranges from 200 to 600 mg taken once a day. Again, the dose should be slowly titrated until the effective dose is achieved. Pediatric patients (2 to 12 years of age) are given an adjusted dose of Lamictal based on the ..., You can't just stop without a doctor. The rash should get you a fast call back. Call a neuro, ASAP. The lamictal rash is a known and risky side effect. I'm sure there's A doctor somewhere, even the ER who can take a call or see you. You may need a new med, but you can't keep taking it with the rash., Lamotrigine is usually taken 1 or 2 times daily with or without food. Typically patients begin at a low dose of medication and the dose is increased slowly over several weeks. The dose usually ranges from 25 mg to 400 mg., For carbamazepine and lamotrigine doses exceeding the upper end of standard dosing (e.g., carbamazepine, greater than 1200 mg/day; lamotrigine, greater than 500 mg/day), we encourage consideration of proactive dose reduction at cenobamate 200 mg/day to prevent potential adverse effects. All dose reductions for adverse effects can be repeated ..., 200-250 mg once per day. 300-400 mg once per day. 400-600 mg once per day. Lamictal XR tablets may be prescribed alone to treat partial-onset seizures in certain adults and children ages 13 ..., Dose reduction q 2 months: carbamazepine 100 mg; oxcarbazepine 150 mg; phenytoin 50 mg; lamotrigine, 25 mg; topiramate, 25 mg; levetiracetam, 250 mg and zonisamide, 50 mg. > 80% of relapse during taper occurred within 2 months of dose reduction. 25% of patients attempting to discontinue AED relapsed., Medications used as mood stabilizers (Lamictal, Tegretol, Depakote, etc.) are actually classed as anticonvulsants. The only true mood stabilizer is lithium. It was wise of your doctor to alert you to the possibility of a seizure, but it's pretty unlikely. I came off lamotrigine over two weeks and had no problems at all., So I started lamictal 9 days ago for a mood disorder but the issue I have pharmacophobia (a phobia of medication) which is making it impossible to function as I am taking new meds. I decided today that I want to stop the lamictal until I deal with my phobia through a psychological intervention before I try again, since I have debilitating ..., It's worth mentioning that my blood pressure has dropped from 170/100 to 140/80 since reducing my lamictal. It causes high blood pressure in some people too. This was destroying my liver and kidneys. If you find this medication is hurting as much (or more) than it's helping please talk to your doctor. DO NOT TAPER LAMICTAL ON YOUR OWN!, Jun 29, 2022 · Lamictal is a drug primarily used as a mood stabilizer. Lamictal is an anticonvulsant drug and is also used for treating seizures and epilepsy. It can be used alone or with other drugs to treat mood disorders and epilepsy. Lamictal Withdrawal Symptoms & Side Effects , My doctor recommended I go down 25mg every couple of days. I'm not 100% sure but I think they have suggested time frames on the page. Little help? I just want to get out of these 50s. So here's me. 17 days, and want out. Days 1-13: (50 mg) (dropped 1 down the drain) Day 14: (100 mg) (Gave me terrible tremors) Days 15-17 (50 mg) , Titration and drug tapering should also be approached differently in most older patients; a valuable general principle is to begin with lower initial starting doses of AEDs, titrate drugs slower, and utlize a lower initial target dose range than generally used in younger patients (i.e., "start low, go slow") . Since elderly patients often ..., Tapering This Time. ... Now, I'm taking Lamotrigine, and I hope it goes better then Depakote. I've only been being treated for Bipolar for a few months, so these classifications of drugs are going to take some getting use to. before this I was on Paxil, Lexapro, and Cymbalta, which was treating anxiety and depression. ..., Agree you need to speak to your healthcare team. But I always taper up 25-50mg per week for a couple of weeks at a time so take it slow if you really are going to do it alone. Hello. I take 200mg of Lamictal and have for a couple of years now. It not helping me or doing a damn thing, except (I think) interfering with my…., The dosing regimen of lamotrigine can depend on which other medications you are taking to treat bipolar disorder and is adjusted when you wean off and discontinue other medications.³ Other factors that may impact the dose are the condition it is prescribed to treat and patient age., A reduction of 20% to 25% of the original dose was recommended as the general taper of lamotrigine. A faster taper was recommended for patients with reduced liver function, patients taking valproic acid, and patients with significant adverse effects. , Lamotrigine seemed to us, and perhaps to many psychiatrists, to have a pharmacologic profile that could be useful for this patient population. A study reported in this issue by Crawford et al. ( 3 ) persuasively documents the disappointing failure of this seemingly promising mood stabilizer to be helpful., Abstract. The process of stopping antipsychotics may be causally related to relapse, potentially linked to neuroadaptations that persist after cessation, including dopaminergic hypersensitivity. Therefore, the risk of relapse on cessation of antipsychotics may be minimized by more gradual tapering. There is converging evidence that …, Lamotrigine is usually taken 1 or 2 times daily with or without food. Typically patients begin at a low dose of medication and the dose is increased slowly over several weeks. The dose usually ranges from 25 mg to 400 mg., 1 interaction. Contraindicated. oxcarbazepine + metoclopramide. contraindicated if seizure disorder use; otherwise, use alternative: combo may alter seizure control; may incr. risk of CNS depression, psychomotor impairment (antagonistic effects, metoclopramide may decr. seizure threshold; additive effects) rilpivirine., A dosing algorithm was used to guide the conversion of 77 patients with epilepsy (16 years of age) from valproate monotherapy through lamotrigine adjunctive therapy at 200mg daily to lamotrigine monotherapy at 500 mg daily in an open-label study comprising a lamotrigine escalation phase (8 weeks), a valproate withdrawal phase (6 weeks), and a ..., Anyway the taper should be very slow. I cut out 25 mg and kept it there for a month. Now I cut out another 25mg. The more you rush it, the worst it gets. Also there is an amino acid which really ..., Safety and efficacy has not been established. With valproic acid (age 2-12 yr) Initial: 0.15 mg/kg/day PO qDay or divided q12hr for 2 weeks, THEN. 0.3 mg/kg/day PO qDay or divided q12hr for 2 weeks. At 5 weeks increase by 0.3 mg/kg q1-2Week to maintenance dose of 1-5 mg/kg/day PO qDay or divided q12hr; not to exceed 200 mg/day., If you feel okay you could try another 10% reduction sooner than the 4 weeks, eg between 2-3 weeks after. I think tapering carefully would be better than risking too fast a taper. Removal of lamotrigine can cause a nasty rebound of "alerting," i.e. anxiety, restlessness, and sleeplessness., I have been seizure free on lamictal for just over 3 years until a month ago. I was taking a prednisone taper pack at the time and I was wondering if this may have caused me to have a breakthrough seizure? My levels really dropped too. Has anyone experienced any interactions between lamictal and prednisone? Any feedback would be greatly appreciated.