Neosporin sulfa allergy

Contraindications & Precautions. We usually instruct our patients that they should separate vaccinations and allergy shots by at least 24 hours because if there were a reaction to one or the other, it wouldn’t be possible to determine which was the cause. This becomes problematic during influenza vaccination season.

Neosporin side effects. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. A rare but serious side effect of neomycin is hearing loss, which has occurred in people using other forms of neomycin. It is unlikely that you would absorb enough ...Two healthcare workers had been reported to have suffered anaphylactic reactions to their Pfizer vaccines in the first week of the COVID-19 vaccine roll-out in December 2020. But, on investigation, there was no scientific basis for concern for the large majority of individuals with food, venom (bees and wasps) or known medicine allergies, even ...eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection ). Common side effects of Tobrex may include: eye itching or redness; mild burning, stinging, or irritation; itchy or puffy eyelids; blurred vision; or. your eyes may be more sensitive to light. This is not a complete list of side effects and others may occur.Nausea or vomiting. Dizziness, feeling lightheaded, or fainting. Stomach cramps. Joint pain. Severe Skin Reactions. Topical silver sulfadiazine can cause severe skin reactions called Stevens ... Z88.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2024 edition of ICD-10-CM Z88.1 became effective on October 1, 2023. This is the American ICD-10-CM version of Z88.1 - other international versions of ICD-10 Z88.1 may differ. Descriptions. Neomycin, Polymyxin B, and Bacitracin is a combination antibiotic medicine used to help prevent infections of the skin. Neomycin, polymyxin B, and bacitracin combination is available without a prescription. This product is available in the following dosage forms: Ointment. Before Using.

If allergic reactions attributable to treatment with silver sulfadiazine occur, continuation of therapy must be weighed against the potential hazards of the particular allergic reaction. ... In the treatment of burn wounds involving extensive areas of the body, the serum sulfa concentrations may approach adult therapeutic levels (8 mg% to 12 mg ...How Neosporin ophthalmic solution works. Neosporin ophthalmic solution is a combination of three different antibiotics that help treat bacterial eye infections.. Neomycin is an aminoglycoside antibiotic that prevents bacteria from making proteins that they need to help them grow and survive.. Polymyxin B is a polypeptide antibiotic and gramicidin is a peptide antibiotic.An allergy shot is a medicine that is injected into your body to treat allergy symptoms. An allergy shot is a medicine that is injected into your body to treat allergy symptoms. An...Sulfa allergy incidence among males and females was found to be 2.23 percent (1.91-2.59) and 3.42 percent (3.13-3.74), respectively. Additionally, sulfa antimicrobials were associated with the highest incidence rates of antimicrobial allergies for both males and females compared to penicillin, cephalosporin, fluoroquinolone, tetracycline ...Patients with documented allergy to sulfonamide antibiotics may be at increased risk of all drug-induced reactions that appear to be allergic in nature, irrespective of drug class. The term “sulfa-allergy” is misleading, restrictive, and should be avoided.Safeguards Are in Place. Everyone who gets a COVID-19 vaccine may be monitored onsite for at least 15 minutes after vaccination. You had an immediate (within 4 hours) allergic reaction that was not severe from a previous dose of that type of COVID-19 vaccine. You've had a non-severe allergic reaction to an ingredient used in the COVID-19 vaccine.

Khan D, Banerji A, Blumenthal K, et al. Drug allergy: A 2022 practice parameter update. J Allergy Clin Immunol. 2022;150(6):1333-1393. Guest Author: Cosby Stone, Jr. MD, MPH is an Assistant Professor of Medicine in the Division of Allergy, Pulmonology, and Critical Care Medicine within the Department of Medicine at Vanderbilt University Medical ...Depending on your symptoms from your allergy, you may have a 30 minute wait. Symptoms of throat swelling, swollen tongue, difficulty breathing, hives over your body require longer wait times. A rash doesn't. 3.There are two types: irritant contact dermatitis and allergic contact dermatitis. In addition to itchy, red rash, both types of contact dermatitis share other symptoms: dry, cracked, or scaly skin ...As best as we can determine, the four best drugs to combat acute bacterial infection in adults are: bacitracin/polymyxin B/neomycin; tobramycin; 0.6% besifloxacin; and 1.5% levofloxacin. In children, we use either generic trimethoprim/polymyxin B …

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Since severe allergic reactions to egg‐based influenza vaccines are rare, the CDC and its Advisory Committee on Immunization Practices (ACIP) guidelines state that individuals with mild egg allergy can receive any licensed and recommended age‐appropriate flu vaccine and no longer need to be observed for 30 minutes after receiving the vaccine.POLYSPORIN® First Aid Antibiotic Ointment is the #1 Dermatologist Recommended First Aid Ointment. It is a double antibiotic, containing Bacitracin and Polymyxin B. It helps prevent infection in minor cuts, scrapes and burns. It does not contain Neomycin. Check for Expiration Date Using POLYSPORIN® past its expiration date is unsafe, risky, and does not guarantee similar effectiveness. Do not ...O: Decreased o xygen-carrying capacity and o ther hematologic abnormalities. Several case reports describe methemoglobinemia in patients taking trimethoprim-sulfamethoxazole. 7, 8 Although this adverse effect is rare, the sulfamethoxazole component can induce methemoglobinemia, which occurs when more than 1% of heme iron exists in the ferric (Fe 3+) redox state, rather than the usual ferrous ...Neosporin: Clinical 2 nd /3 rd degree burns : Polymyxin B: Clinical 2 nd /3 rd degree burns : Nitrofurazone: Clinical 2 nd /3 rd degree burns : ... (Silvadene) for burn patients with a sulfa allergy. Bacitracin zinc is effective to promote regenerative healing when topically applied to wounds in concentrations from about 5% to 8%.

POLYSPORIN® First Aid Antibiotic Ointment is the #1 Dermatologist Recommended First Aid Ointment. It is a double antibiotic, containing Bacitracin and Polymyxin B. It helps prevent infection in minor cuts, scrapes and burns. It does not contain Neomycin. Check for Expiration Date Using POLYSPORIN® past its expiration date is unsafe, risky, and does …Neosporin is an ointment that contains three types of antibiotics: neomycin, polymyxin, and bacitracin.This ointment is available over-the-counter, and people commonly use it to prevent skin ...Joint Infections. S. aureus is a major pathogen in joint infections. Although there is limited evidence regarding treatment, it usually is managed using drainage combined with a four-week course ...We have a variety of NEOSPORIN® antibiotic products that may meet your needs: If allergic to Neomycin Sulfate, we recommend using our Neomycin-free products: SIMPLY NEOSPORIN™ or POLYSPORIN®, which contain double antibiotic drugs, Bacitracin Zinc and Polymyxin B Sulfate.1,071 Posts. Specializes in School Nurse. May 31, 2018. Neosporin & triple antibiotic cream has sulfa in it so some students may have an allergic reaction. Soap & water is the standard for basic first aid. No crutches - parents provide. Cough drops are just not effective. JenTheSchoolRN, BSN, RN.kidney problems--swelling, urinating less, feeling tired or short of breath. Common side effects of neomycin may include: nausea, vomiting; or. diarrhea. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.Adverse reactions to sulfonamides are common. In review of electronic health records (EHR) of three large health systems in the United States (US), an allergy to sulfonamide antibiotics was labeled in 5.1-7.4% of patients [2, 34, 35].In the Partners HealthCare System cohort, sulfonamide antibiotics were the 2nd leading cause of immediate and non-immediate hypersensitivity reactions behind ... Sulfa-based eye drops like Genoptic (gentamicin sulfate), Polytrim (polymyxin B/trimethoprim), atropine sulfate, and Maxitrol (neomycin/dexamethasone/polymyxin B) are safe to use in those with reported sulfa allergies. Can you use Neosporin If you have a sulfa allergy? No. None of the ingredients are sulfanomide (sulfa) antibiotics.

Allergic contact dermatitis is the most frequent reaction associated with aminoglycosides, particularly topical neomycin for which patch testing can be useful and is validated. Clindamycin is most commonly associated with delayed maculopapular exanthems for which patch testing may be helpful but is not validated. IgE-mediated reactions and ...

Neomycin is an aminoglycoside antibiotic that displays bactericidal activity against gram-negative aerobic bacilli and some anaerobic bacilli where resistance has not yet arisen. It is generally not effective against gram-positive bacilli and anaerobic gram-negative bacilli. Neomycin comes in oral and topical formulations, including creams, ointments, and eyedrops.Jan 18, 2009 · I actually just went through this same thing. If you read the label, you'll see that the antibiotic used in the ointment is a sulfa based drug. Sulfa has one of the highest allergic reactions of all the antibiotics. If you've ever been told you're allergic to sulfa, you're also allergic to the antibiotic ointments. This topic will discuss the allergy evaluation of patients with past immediate reactions to cephalosporins, including skin testing and graded challenges. Patients with immediate reactions to a specific cephalosporin in the past may require subsequent treatment with a different cephalosporin or a related antibiotic, such as a penicillin ...One way is to perform a skin test. And, assuming the skin test is negative, give the patient a dose of penicillin to prove they are not allergic, said Dr. Khan. "At the end of the day, we can determine whether they truly are tolerant of penicillin, which is again the vast majority of the time," said Dr. Khan. Read more about other ways to ...Medscape - Indication-specific dosing for Neosporin Original Ointment, Triple Antibiotic Ointment (neomycin, polymyxin B, bacitracin topical), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. ... Allergic cross-reactions may occur which could prevent use of ...This article provides a descriptive bibliographic review to update information on sulfa allergy, its prevalence, management, and recommendations to prevent such …Subtotal. $43.70. FR - TVA réduite de 5.5% (5.5%) $2.28. Tax. $2.28. Proceed to Checkout. The usual application timetable involves taking this drug from 2 to 4 times daily, depending on the type of condition you have and exactly how intense it is Bactrim (sulfamethoxazole and trimethoprim) is a combination drug made use of for the procedure of ...Penicillin allergy is the most commonly reported drug allergy in the United States. Although penicillin allergy is widely reported, 80% to 90% of individuals with self-reported penicillin allergy are actually able to tolerate penicillins after undergoing evaluation for penicillin allergy. Because most patients with self-reported penicillin allergy will have subsequent negative allergy testing ...Can my child who has an allergy (hives) to polymixin b sulfate/trimethoprim opthalmic drops do fine with neosporin? A doctor has provided 1 answer A member asked:A sulfa allergy occurs when a person has an allergic reaction to drugs that contain chemicals called sulfonamides. Symptoms may include a rash, difficulty breathing, and more. Sulfa is present in ...

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Sulfite Sensitivity. Sulfites can trigger asthma attacks and allergic reactions. Symptoms include wheezing, shortness of breath, coughing, sneezing and skin reactions. Rarely, sulfite allergies can lead to anaphylaxis. Certain foods, beverages and medications contain sulfites. People with asthma are more likely to have reactions to sulfites.The serious allergic reaction cases reported outcomes that required emergency department visits or hospitalizations to receive drug and other medical treatments.Depending on your symptoms from your allergy, you may have a 30 minute wait. Symptoms of throat swelling, swollen tongue, difficulty breathing, hives over your body require longer wait times. A rash doesn't. 3.Silver sulfadiazine cream is used to prevent and treat wound infections in patients with second- and third-degree burns. Patients with severe burns or burns over a large area of the body must be treated in a hospital. Silver sulfadiazine is an antibiotic. It works by killing the bacteria or preventing its growth.Location: USA. Posts: 140. Re: does neosporin have sulfa in it? My GP told me that 80% of the population is allergic to Neosporin and doesn't have a clue. I don't use it anymore. I had an allergic reaction (dermatitis) to it while trying to treat an infection caused by fire ant bites.Mar 28, 2018 · A sulfa allergy occurs when a person has an allergic reaction to drugs that contain chemicals called sulfonamides. Symptoms may include a rash, difficulty breathing, and more. Sulfa is present in ... Specialist consultation might also be helpful, as several desensitization protocols for sulfonamides are described in the literature. 2, 8 A comprehensive approach to difficult cases involving sulfa allergies is shown in Figure 1. Figure 1. Approach to prescribing sulfa nonantibiotics for patients with sulfa allergy.Unfortunately, stating that you have an allergy to a "sulfa" drug is quite ambiguous and essentially misleading. It is a term used very broadly and if you are sensitive or allergic to "sulfa" drugs, it doesn't mean that you cannot use anything that contains sulfur. Cortisporin ( Hydrocortisone; Neomycin; Polymyxin B) does have sulfur-containing ...Jun 1, 2010 · Neosporin: Clinical 2 nd /3 rd degree burns : Polymyxin B: ... It is a good alternative to silver sulfadiazine (Silvadene) for burn patients with a sulfa allergy ... Jun 12, 2020 · Patients with documented allergy to sulfonamide antibiotics may be at increased risk of all drug-induced reactions that appear to be allergic in nature, irrespective of drug class. The term “sulfa-allergy” is misleading, restrictive, and should be avoided. Rare but serious allergic reactions, including fatal anaphylaxis, have been reported with the antiseptic chlorhexidine gluconate. These reactions can occur within minutes of exposure, and can ... Common side effects of Triple Antibiotic may include: mild itching or rash; or. minor skin irritation after using the medicine. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Triple Antibiotic side effects (more detail) ….

Neomycin sulfate is an antibiotic commonly used in many prescription and over-the-counter antibacterial topical creams, powders and ointments, eye drops, and vaginal suppositories. It is also commonly found in dental and veterinary care products. Cross-reactivity may occur to other related aminoglycoside antibiotics, such as kanamycin ...POLYSPORIN® First Aid Antibiotic Ointment is the #1 Dermatologist Recommended First Aid Ointment. It is a double antibiotic, containing Bacitracin and Polymyxin B. It helps prevent infection in minor cuts, scrapes and burns. It does not contain Neomycin. Check for Expiration Date Using POLYSPORIN® past its expiration date is unsafe, risky, and does not guarantee similar effectiveness. Do not ...If you're allergic to penicillin or sulfa antibiotics, Neosporin Plus Pain Relief ointment is safe for you to use since the formula in this medication doesn't contain either type of antibiotic. But if you're allergic to medications such as gentamicin (Gentak) , streptomycin, and paromomycin , talk to your provider first before using Neosporin ...medically, im not sure, but for myself having a sulfa allergy i have found that neosporin, or the ingredients therein, do make me break out in an itchy type rash. Wiki User. ∙ 12y ago.However, if the patient has a history of a severe allergy (eg, Stevens-Johnson syndrome, toxic epidermal necrolysis), TMP-SMX should be avoided and desensitization should not be performed. (See "Treatment and prevention of Pneumocystis infection in patients with HIV", section on 'Desensitization for patients with a sulfa allergy' and ...Neosporin is like Polysporin in the sense that it is a popular antibiotic ointment designed to prevent infection in minor cuts and wounds. However, the key difference between two lies in its formula. Neosporin contains three active ingredients (vs. two for Polysporin), the duo of polymyxin B and bacitracin, as well as, neomycin.However, the highly specialized allergy centers in Denmark have gained permission from the Danish Health Authority to offer the JJ vaccine to patients with PEG allergy based on a medical assessment and risk evaluation including the risk of severe COVID‐19 disease, the risk of severe side effects including vaccine‐induced immune thrombotic ...Jun 13, 2023 · A SULF-FAST score of <3 had lower than 5% risk for a hypersensitivity reaction, whereas a score of ≥3 was associated with >20% risk for a reaction. Although this tool requires further validation, it gives us some direction for choosing patients in whom TMP-SMX oral challenges are safe, namely patients with mild cutaneous reactions or more ... Neosporin sulfa allergy, Neosporin is the one that most people have heard of, it has great brand-name recognition. However, most dermatologists do not recommend using Neosporin. Neosporin contains a mixture of 3 topical antibacterial medications: Neomycin, polymixin, and bacitracin. Neomycin is one of the most common causes of an allergic contact dermatitis., Lexi-comp (online.lexi.com) has a drug allergy and idiosyncratic reactions database that is searchable by drug class. For example, for levofloxacin allergy search "fluoroquinolone allergy." There is also a review of penicillin cross reactivity under "penicillin allergy." Figure: Penicillin Core Structure Selected References: 1., Neomycin frequently causes allergic reactions of the skin called contact dermatitis. It can cause the skin to become red, scaly, and itchy. The more Neosporin you use, the worse the skin reaction gets. Neomycin is such a common allergen that it was named Allergen of the Year in 2010. The goal of this award is to bring awareness to commonly used ..., Cephalexin is a cephalosporin-type antibiotic that may be used in the treatment of infections caused by susceptible gram-positive bacteria. Approximately 10% of people who are allergic to penicillin will be allergic to cephalexin. 5. Tips. Can be taken with or without food. Take exactly as directed and for the duration intended., Bacitracin is a polypeptide antibiotic.It is a mixture of related cyclic peptides produced by Bacillus licheniformis bacteria, that was first isolated from the variety "Tracy I" (ATCC 10716) in 1945. These peptides disrupt gram-positive bacteria by interfering with cell wall and peptidoglycan synthesis.. Bacitracin is primarily used as a topical preparation, as it can cause kidney damage when ..., Allergists are consulted about the question of hypersensitivity to loop or thiazide diuretics in patients with a history of sulfonamide allergy because it is thought that there is a risk of cross-reactivity from common sulfonamide constituents of these compounds. In text references and drug-package inserts, reference is made to this risk., Safeguards Are in Place. Everyone who gets a COVID-19 vaccine may be monitored onsite for at least 15 minutes after vaccination. You had an immediate (within 4 hours) allergic reaction that was not severe from a previous dose of that type of COVID-19 vaccine. You've had a non-severe allergic reaction to an ingredient used in the COVID-19 vaccine., Other types of sulfa medications may trigger a reaction in some people who have a sulfonamide antibiotic allergy: 1. Sulfasalazine (Azulfidine), used to treat Crohn's disease, ulcerative colitis and rheumatoid arthritis 2. Dapsone, used to treat leprosy, dermatitis and certain types of pneumonia Keep in mind that if … See more, In children with minor skin infections (e.g., impetigo) or secondarily infected lesions (e.g., eczema, ulcers, lacerations), treatment with mupirocin 2% topical cream (Bactroban) is recommended ..., problems with balance or eye movement; or. loss of bladder or bowel control. Call your doctor at once if you have a high fever. Common Shingrix side effects include: headache, muscle pain; feeling tired; stomach pain, nausea, vomiting, diarrhea; fever, shivering; or. pain, redness, or swelling where the shot was given., Children: 10 mg per kg IV every 6 hours. Parenteral drug of choice for MRSA infections in patients allergic to penicillin; 7- to 14-day course for skin and soft tissue infections; 6-week course ..., MA. Marvell 5 Jan 2010. If you are allergic to the actual antibiotic neomycin, then it is fine as the H1N1 and other Flu shots don't have the antibiotic. Sometimes people are just sensitive and can have allergies to other things, in this case you can have the shots but there is a possibility of having allergic reactions., Diagnosis. Treatment. An adhesive allergy is a form of contact dermatitis in which a person experiences an allergic reaction to topical glues used in products like adhesive bandages, artificial nails, transdermal patches, and continuous glucose meters. Allergic contact dermatitis occurs when the skin touches something that a person is allergic ..., Find patient medical information for Neosporin (neo-bac-polym) topical on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings., Sulfa Vs Sulfite Allergy. Sulfa allergies and sulfite allergies arent the same thing. Sulfites occur naturally, or are used as a preservative agent in some foods and drinks. Sulfa medications and sulfites found in food and drink arent related to each other. The similarity between their names can cause some confusion. Read more about the ..., A Decision Tool for Sulfonamide-Antibiotic Allergy. David J. Amrol, MD, reviewing Waldron JL et al. JAMA Netw Open 2023 Jun 5. A scoring system was reasonably good at predicting hypersensitivity reactions. Allergies to sulfonamide antibiotics (e.g., sulfamethoxazole-trimethoprim [TMP-SMX]) are notorious for causing drug hypersensitivity ..., Although around 3% of the population report a "sulfa allergy", studies show that only 3% of these patients have true hypersensitivity [ 3, 4 ]. Sulfonamide antibiotic reactions encompass the entire spectrum of hypersensitivity reactions (types 1-4). Type 1 hypersensitivity is IgE-mediated and may include an anaphylactic sequelae., Lexi-comp (online.lexi.com) has a drug allergy and idiosyncratic reactions database that is searchable by drug class. For example, for levofloxacin allergy search “fluoroquinolone allergy.” There is also a review of penicillin cross reactivity under “penicillin allergy.” Figure: Penicillin Core Structure Selected References: 1. , Abstract. Purpose of review: The goal of this article is to provide an updated understanding and evidence-based approach where possible for antifungal hypersensitivity. This includes recognition of clinical phenotype, implications for cross-reactivity and diagnostic, and management strategy for immediate and delayed hypersensitivity reactions ..., Allergic Contact Dermatitis and MoreWhen bacitracin causes cell-mediated ACD (ie, a local delayed hypersensitivity phenomenon 10), reactions may include urticaria, swelling, redness, cellulitis, and poor healing.Patients often confuse these with normal or abnormal healing, and so do clinicians. One subtle hint indicates that ACD is more likely than poor healing: ACD is more likely to cause ..., If you could please call us at 1-800-223-0182, we're open Monday through Friday, 8 AM-8 PM EDT. We hope to hear from you soon. 1-8 of 87 Reviews. . Learn about how NEOSPORIN® + Pain Relief Products can help soothe painful cuts, scrapes, and burns, while also preventing infection., Lexi-comp (online.lexi.com) has a drug allergy and idiosyncratic reactions database that is searchable by drug class. For example, for levofloxacin allergy search "fluoroquinolone allergy." There is also a review of penicillin cross reactivity under "penicillin allergy." Figure: Penicillin Core Structure Selected References: 1., can you take sulfa drugs?? I know some doctors recommend polysporin vs the neosporin. Here is something I copied from a website-"Neosporin contains Neomycin sulfate-3.5mg, Bacitracin-400 units and Polymyxin B 5000 units. Of course it does contain cocoa butter, olive oil may prevent the formation of scars. A 1/2 oz tube costs $5., They can increase the absorption of the drug, which can cause harmful effects. Apply only small amounts of neomycin to scrapes, cuts, burns, sores, and wounds, and do not apply it more frequently than directed. Neomycin can be absorbed into the body through broken skin and cause kidney problems and hearing difficulty., For otic dosage form (ear drops): For ear canal infection: Adults—4 drops into the affected ear 3 or 4 times a day. Children—3 drops into the ear 3 or 4 times a day. For mastoid cavity infection: Adults—4 to 10 drops in the ear every 6 to 8 hours. Children—4 or 5 drops in the ear every 6 to 8 hours., This topic will discuss the allergy evaluation of patients with past immediate reactions to cephalosporins, including skin testing and graded challenges. Patients with immediate reactions to a specific cephalosporin in the past may require subsequent treatment with a different cephalosporin or a related antibiotic, such as a penicillin ..., A search of high-quality studies on the use of silver in wound care was performed on PubMed. A detailed qualitative analysis of published articles was performed to evaluate the evidence for the use of silver in infected wounds, clean wounds, burns, and over closed surgical incisions. Fifty-nine studies were included in this qualitative analysis., Use a temporary or permanent screen to get more fresh air without all the pollen. The feeling of a warm breeze on a spring day is something many allergy sufferers have had to go wi..., Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency. i have a sulfa allergy. is if safe to take levaquin?: Levaquin: Levaquin is not a sulfa drug. It belongs to the group of an., Sulfa drug allergy is one word holding the whole cross-reactivity theory in it. It should be obsolete from the medical dictionary. This one word is complicating the medical decision-making. Allergies should not be attributed to classes or groups of drugs unless proven. After reviewing all the available literature we can conclude that ..., Answers. E-mycin (erythromycin) is a MACROLIDE antibiotic and Neomycin is an AMINOGLYCOSIDE antibiotic. Even though they sound similar they are in no way related and you will not be allergic to Neomycin despite your e-mycin allergy. If you are allergic to neomycin you should not receive the shingles vaccine. From the information you have given ..., Erythromycin - inhibits bacterial protein synthesis. Mafenide - interferes with bacterial folic acid synthesis. Mupirocin - inhibits bacterial protein synthesis. Retapamulin - inhibits bacterial protein synthesis. Silver sulfadiazine - acts against bacterial cell wall and cell membrane. Sulfacetamide - inhibits bacteria's ability ..., Hypersensitivity reactions including IgE-mediated and delayed cell-mediated reactions to aminoglycosides, clindamycin, linezolid, and metronidazole are rare. For aminoglycosides, allergic contact dermatitis is the most frequent reaction for which patch testing can be a useful step in evaluation. For clindamycin, delayed maculopapular exanthems are the most common reactions. There are case ...